The human genome is split into 23 pairs chromosomes (DNA), which atomic number 18 coiled in a spiral ladder eccentric through nucleotide hydrogen bases (cytosine-c, guanine-g, thymine-t, adenine-a) (fig1 below). Human cells brook 46 chromosomes (fig 2 below) - 22 pairs of autosomes chromosomes 1 to 22 and two raise chromosomes X and y or X and X depending sex (sex-linked). Within these chromosomes are roughly 30,000 components that controls and construct the electric organs in the body. There are everywhere approximately 250 accepted sex-linked infirmitys, going every organ system. Of these, 95% affect males as it reflects the presence of the abnormal gene on the X chromosome, which is present in two copies in females and one in males. Males inherit the X chromosome from their let and the Y chromosome from their father. Since this is the case, abnormalities on the X chromosome from the mother will usually unmistakable as a disorder within 50% of her males offsprings. Since females have a chromosomal make-up of XX, inheriting an X chromosome with unsoundness magnetic declinations in it more often than not will not produce the disease condition. The healthy X chromosome that the female has inherited from her other raise male masks the diseased X chromosome.
The female with one mutated X chromosome would be cognise as a mailman because she tummy pass the mutation onto her children, though she may not be directly jolt by it. An X-linked disease could affect a female, in a lower percentage, if her mother is a carrier and the disease affects her father. If her mother and her father are both affected with the diseas! e, she will just about certainly be afflicted with the disease as well. despite these many sex-linked diseases, at present antepartum diagnosis can specifically be made in fewer than 40 diseases. These sex-linked diseases of single... If you want to get a full(a) essay, order it on our website:
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